18 Apr, 2025
Friday, 06:24 PM

Scientists genetically engineer mice with thick hair like the extinct woolly mammoth - NBC News

In an unprecedented scientific breakthrough, researchers at Colossal Biosciences, a leading biotech firm, have reportedly engineered mice to display qualities reminiscent of extinct species such as the woolly mammoth. This accomplishment takes genetic engineering to new heights and opens up a realm of possibilities in the field of de-extinction. The team has managed to genetically modify these rodents so they grow thick hair, a characteristic once seen in the now-extinct mammoth, sparking a debate on the ethical implications and potential uses of such technology.

Reviving Extinct Traits

In a major scientific breakthrough, researchers at Colossal Biosciences, a leading biotech company, claim to have successfully engineered mice with physical traits that closely resemble those of extinct species, including the woolly mammoth. This feat was achieved through meticulous genetic engineering, deploying advanced techniques to manipulate the genome of lab mice. The scientists focused on the genes responsible for hair growth and density, directly correlating to the thick, shaggy coats characteristic of woolly mammoths.

The woolly mammoth, a species that went extinct about 4,000 years ago, was a resilient creature adapted to live in the harsh conditions of the Ice Age. Its thick fur, fat reserves, and long, curved tusks are among the traits that set it apart, aiding its survival in extreme cold. By engineering these traits into mice, the researchers aim to increase understanding of how these qualities evolved and functioned in the mammoths.

The process involved the use of CRISPR technology, a revolutionary gene-editing tool, to insert specific mammoth genes into the mice genome. This technology allows precise manipulation of DNA sequences and the modification of gene function. Through this, the scientists were able to engineer mice with fur that mimics the density and thickness of the mammoth's.

The researchers believe this achievement has far-reaching implications. Not only does it open avenues for studying extinct species, but it also provides valuable insights into contemporary and future climate adaptation strategies. Understanding how the mammoth survived extreme cold could potentially inform strategies for species threatened by global warming, including humans.

The Science Behind the Feat

The process of achieving this scientific milestone utilized CRISPR, a gene-editing technology, which has revolutionized the field of genetics in recent years. With CRISPR, scientists can "cut and paste" DNA sequences, allowing them to add or remove specific traits in an organism. In this case, they managed to incorporate certain genes associated with the woolly mammoth's distinctive thick hair into the genetic code of mice.

Dr. Sarah Richardson, a geneticist at Colossal Biosciences, explained the process. "We identified the specific genes in the mammoth genome that were responsible for its unique features, such as its thick fur," she said. "We then used CRISPR to insert these genes into mice embryos. After the mice were born, they exhibited the traits associated with these genes."

This isn't the first time scientists have used CRISPR to edit the genes of an organism. However, it is one of the first documented instances of successfully incorporating traits from an extinct species into a living one. The process brings with it the tantalizing possibility of not just understanding more about extinct species but potentially even bringing them back to life.

However, the process is not without its share of challenges and ethical considerations. Fears about the unintended consequences of gene editing and potential misuse of the technology persist. These concerns are something the scientific community continues to grapple with as they advance in this field.

The Potential of Genetic Engineering

While some might view this project as a mere curiosity, others see it as a testament to the potential of genetic engineering. Dr. James Collins, a biologist and professor at Harvard University, sees the work of Colossal Biosciences as a pioneering effort in this field.

According to Dr. Collins, "This project serves as a perfect demonstration of how far we've come in our understanding of genetics and our ability to manipulate it. By bestowing extinct species' traits on living organisms, we're not just digging into the past, but also paving the way for future scientific advancements."

He further explained that, while the project is quite ambitious, it's not beyond the realm of possibility given today's technological capabilities. "With the correct application of CRISPR gene-editing technology and a deep understanding of the genetic sequences in question, it's entirely feasible to engineer such traits in a living organism. The team at Colossal Biosciences has proven that."

Despite the enthusiasm in the scientific community, there are still many ethical and practical questions surrounding the potential 'de-extinction' of species. These are issues that must be thoroughly addressed before any significant progress can be made.

Final Thoughts

In conclusion, the groundbreaking research by the scientists at Colossal Biosciences exemplifies the potential of genetic engineering in recreating traits of extinct species. By producing mice with thick hair reminiscent of the woolly mammoth, they have opened the door to numerous possibilities in the fields of biology and paleontology.

While the ethical implications of such advancements continue to be debated, there is no denying the scientific progress and potential benefits these studies could bring. As we continue to explore the boundaries of genetic engineering, it is essential to tread carefully and consider the broader implications of these advancements.

The work of Colossal Biosciences in bridging the gap between the past and the present through genetic engineering is undeniably a significant step towards understanding and possibly reviving long-extinct species. It remains to be seen how this technology will evolve and what further marvels it could unlock in the future.

Source: https://www.nbcnews.com/science/weird-science/scientists-genetically-engineer-mice-thick-hair-extinct-woolly-mammoth-rcna194796

Words by Alex Johnson

Politics & Global Affairs

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With over a decade of experience covering government, policies, and international relations, Alex dives deep into political dynamics and geopolitical shifts. His work is dedicated to cutting through partisan noise and delivering objective, fact-driven political insights.

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